ea0037ep293 | Calcium and Vitamin D metabolism | ECE2015
Pepe Jessica
, Mezzaroma Ivano
, Fantauzzi Alessandra
, Falciano Mario
, Salotti Alessandra
, Di Traglia Mario
, Diacinti Daniele
, Belcastro Sara
, Piemonte Sara
, Cipriani Cristiana
, Minisola Salvatore
Introduction: The best repletion and maintenance dosing regimens with cholecalciferol in vitamin D deficient HIV-1 patients remain unknown. Protease inhibitors (PIs) have been shown to inhibit vitamin D 1α- and 25α-hydroxylation in hepatocyte and monocyte cultures. We therefore evaluated the effect of a single high dose of cholecalciferol in vitamin D deficient HIV-1 postmenopausal women undergoing treatment with highly Active Anti-Retroviral Therapy (cART), with and...